The Apothecary Diaries Season 2 Episode 21: Release Date, Where to Watch and More

Maomao just got herself into some deep trouble with the woman named Shenmei, but thankfully, Shisui came to her aid, but not as Shisui, but as Loulan? Yes, the latest episode of The Apothecary Diaries Season 2 has some huge plot twists, thanks to which Maomao will go unpunished, and can even work as an apothecary instead of having to laze around the whole day.

In this article, we’ll recap what happened in episode 20 of The Apothecary Diaries. We’ll also cover everything you need to know about the release of episode 21. We urge you to watch the latest episode, as it is vital to keep up with the plot.

1. Release Date of Episode 21 of The Apothecary Diaries Season 2

Episode 21 of The Apothecary Diaries Season 2 will be released on Friday, June 6, 2025. You can watch the anime on Crunchyroll.

I. Is The Apothecary Diaries on Break This Week?

No, The Apothecary Diaries Season 2 is not on a break this week. Episode 21 is not delayed and will be released on the above-stated date.

2. Recap of Episode 20 of The Apothecary Diaries Season 2

Apothecary Diaries season 2 episode 21
Shenmei berates Suirei | Source: TOHO Animation

Shenmei was furious about Maomao and Kyou-u being at their secret research quarters. She immediately slapped Suirei and blamed her for not protecting the shack from outsiders. She then ordered her to have Maomao strapped to a pillar to have her whipped, but on hearing this, Maomao knew that Shenmei would want to “accidentally” kill her between the punishment, as she saw the feifa production.

As luck would have it, Loulan stepped in and told Shenmei not to punish Maomao, as she was the replacement for the apothecary who had recently died, and she’d be working on perfecting the medicine for immortality. She even told her that Maomao was over thirty years old but couldn’t age as a consequence of the countless experimentation on her body.

The weirdest thing about this situation was that Loulan actually spoke, and she had Shisui’s voice. Maomao connected the dots and understood that Shisui had perfectly fooled everyone in the palace, including Maomao herself. At this point, a lot of Shisui’s and Loulan’s specific traits in the palace made a lot more sense, but none of this mattered anymore as she saved Maomao’s life.

Maomao: Apothecary Diaries season 2 episode 21
Maomao starts working as an apothecary in the cellar | Source: TOHO Animation

Maomao was then locked in a cellar with a lot of medicines to work her magic, along with the notes of a very learned apothecary who had mysteriously died (very likely killed under Shenmei’s instructions). She could only leave her cellar once a day to report to Shenmei on her progress with the elixir of immortality. Maomao wasn’t held at gunpoint or anything, though, and she had the freedom to research at her own pace, and not research at all, and Shenmei would be displeased, but would still not harm her, at least as of now.

It is worth mentioning here that Kyou-u’s mother, who was mentioned in the previous episode, is likely a prostitute of sorts and worked under Shenmei’s instructions. Kyou-u is obviously in the dark about this and is under the impression that his mother is working hard for Shenmei. Maomao speculated that his mother might already be dead at this point, which is probably why Kyou-u was kept away from his mother for such a long time.

Lakan and Jinshi: Episode 21
Lakan is furious with Jinshi | Source: TOHO Animation

Meanwhile, in the Rear Palace, Lakan was furious, and he took all his fury out on Jinshi. He already knew that Shishou was planning on waging war against them, and he was disappointed with Jinshi for not taking any action to save Maomao. This is a really interesting situation as Lakan was fully aware of Jinshi’s true identity, and knew that Jinshi didn’t have the guts to exercise his authority, and discard the identity of “Jinshi the Eunuch”. Amid this argument, Luomen dropped by, calmed Lakan down, and asked him to be respectful while asking for a favor.

3. What To Expect In Episode 21 of The Apothecary Diaries Season 2

The latest episode of The Apothecary Diaries Season 2 has made it clear that the Emperor will be going to war against Shishou’s country. After Lakan was done with his tantrum, he bowed down to Jinshi, addressed him as the moon prince, and asked him to wage war against their enemies. Meanwhile, Maomao has also reached the truth about Jinshi’s identity and realised that he clearly wasn’t just any high-ranking official in the palace.

The upcoming episode of The Apothecary Diaries Season 2 will likely reveal Jinshi adorning his true title, which will be followed by a glimpse of their preparation for war, the post credit scene of the latest episode of the anime has revealed that Maomao is up to no good yet again, and to know more about this, we recommend you to stay tuned for the next episode.

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4. About The Apothecary Diaries

‘The Apothecary Diaries’ is a light novel series written by Natsu Hyuga and illustrated by Touko Shino. The series will be receiving an anime adaptation in 2023.

The story follows a young girl, Maomao, who is the daughter of an apothecary and possesses an extensive knowledge of medicine and herbs. When she is kidnapped and sold to the rear palace, she is forced to navigate life in this new, foreign environment.

 

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